NMDAR2C antibody, GRIN2C antibody, Glutamate receptor subunit epsilon-3 antibody

Primary Antibodies

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSN00038W

$240USD

ID Tag

Rb1181-260909-WS

Immunogen

A synthetic peptide from 2d cytoplasmic domain of human NMDAR2C (GRIN2C) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

NMDAR2C_HUMAN

Also known

NMDE3, Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NR2C, GRIN2C

Target

FUNCTION: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction âº synapse âº postsynaptic cell membrane; Multi-pass membrane protein.
Tissue specificity: Mainly in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Lin Y.J, et al. Brain Res. Mol. Brain Res. 43:57-64(1996)
2. Zody M.C, et al. Nature 440:1045-1049(2006)

Limitation

For research use only

Code

OSN00038W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for NMDAR2C.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSN00038W