Code
OSC00185W
$260USD
ID Tag
Rb1188-260909-WS
Immunogen
A synthetic peptide from 2d cytoplasmic domain of mouse Connexin-57 (CX57, CXA10) conjugated to blue carrier protein was used as the antigen.
Accession
Also known
CXA10, Gap junction alpha-10 protein, Connexin-57, Connexin57, Connexin 57, CX57, GJA10, Connexin 62
Target
FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning.
Tissue specificity: Low levels were detected in skin, heart, kidney, testis, ovary, intestine. Expression not detected in brain, sciatic nerve or liver.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cell junction ⺠gap junction
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Manthey D, et al. J. Biol. Chem. 274:14716-14723(1999)
Limitation
For research use only
Code
OSC00185W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Connexin57.
Spcs X-react.
Mouse. Other species not yet tested but expected to work in human.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.