Code
OSS00203W
$240USD
ID Tag
Rb1158-260909-WS
Immunogen
A synthetic peptide from aa region 220-270 of human 5HT6 R conjugated to blue carrier protein was used as the antigen.
Accession
Also known
5HT6R, 5-hydroxytryptamine receptor 6, 5-HT-6, Serotonin receptor 6, HTR6
Target
FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Expressed in several human brain regions, most prominently in the caudate nucleus.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Kohen R, et al. J. Neurochem. 66:47-56(1996)
Limitation
For research use only
Related
products
Code
OSS00203W
$240USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by the recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for 5HT6R receptor.
Spcs X-react.
Human, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.