5HT3D antibody, Serotonin receptor 3D antibody, 5-HT-3D antibody, 5-HT3D antibody, 5HT3E antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSS00194W

$240USD

ID Tag

Rb1149-260909-WS

Immunogen

A synthetic peptide from c-terminal region of human 5HT3D receptor (Serotonin receptor 3D) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in 5HT3E.

Accession

5HT3D_HUMAN
5HT3E_HUMAN

Also known

5-hydroxytryptamine receptor 3D, 5-HT3D, Serotonin receptor 3D, HTR3D; 5-hydroxytryptamine receptor 3E, 5-HT3E, Serotonin receptor 3E, HTR3E

Target

FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Subcellular location: Cell membrane; Multi-pass membrane protein. Note: Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
Tissue specificity: 5HT3D: Expressed in liver, as well as fetal and adult colon and kidney. 5HT3E: Expressed in adult colon and intestine.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Niesler B, et al. Gene 310:101-111(2003)
2. Niesler B, et al. Mol. Pharmacol. 72:8-17(2007)
3. Karnovsky A.M, et al. Gene 319:137-148(2003)

Limitation

For research use only

Code

OSS00194W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for 5HT3D, 5HT3E receptors.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSS00194W