Code
OSS00188W
$240USD
ID Tag
Rb1143-260909-WS
Immunogen
A synthetic peptide from c-terminal region of human 5HT2A receptor conjugated to blue carrier protein was used as the antigen.
Accession
Also known
5-hydroxytryptamine receptor 2A, 5-HT-2A, 5-HT-2, Serotonin receptor 2A, HTR2A, HTR2
Target
FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Subcellular location: Cell membrane; Multi-pass membrane protein. Note: Localizes to the post-synaptic thickening of axo-dendritic synapses
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Dunham A, et al. Nature 428:522-528(2004)
Limitation
For research use only
Code
OSS00188W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for 5HT2A receptor.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.