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Code
OSR00341W
$240USD
ID Tag
Rb1080-020809-WS
Immunogen
A synthetic peptide from internal region of mouse Runx2 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in human and rat.
Accession
Also known
Aml3, Cbfa1, Osf2, Pebp2a, Core-binding factor subunit alpha-1, CBF-alpha-1, Acute myeloid leukemia 3 protein, Oncogene AML-3, Polyomavirus enhancer-binding protein 2 alpha A subunit,PEBP2-alpha A, PEA2-alpha A,SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit,Osteoblast-specific transcription factor 2, OSF-2
Target
FUNCTION: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. Inhibits MYST4-dependent transcriptional activation.
Tissue specificity: Specifically expressed in osteoblasts.
Tissue specificity: Specifically expressed in osteoblasts.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Mundlos S, et al. Cell 89:773-779(1997)
Limitation
For research use only
Code
OSR00341W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
WB. A dilution of 1 : 1000 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Runx2.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSR00341W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to Runx2
