Neuroligin 3 antibody, Neuroligin-3 antibody, Neuroligin3 antibody, NLGN3 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSN00036W

$240USD

ID Tag

Rb1114-130909-WS

Immunogen

A synthetic peptide to extracellular domain of human Neuroligin-3 (NLGN3) conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.

Accession

NLGN3_HUMAN
NLGN3_HUMAN
NLGN3_RAT
NLGN2_MOUSE

Also known

NLGN3, NL3

Target

Function: Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. May play a role in formation or maintenance of synaptic junctions. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. Defects in NLGN3 may be the cause of susceptibility to X-linked Asperger syndrome 1 (ASPGX1). ASPGX1 is considered to be a form of childhood autism.
Subcellular location: Membrane; Single-pass type I membrane protein
Tissue specificity: Expressed in olfactory bulb and olfactory epithelium. Found in olfactory ensheathing glia but not in olfactory neurons, and in developing peripheral glia.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Carninci P, et al. Science 309:1559-1563(2005)
2. Gilbert M, et al. Glia 34:151-164(2001)
3. Ballif B.A, et al. J. Proteome Res. 7:311-318(2008)

Limitation

For research use only

Code

OSN00036W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for NLGN3.

Spcs X-react.

Human, rat, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSN00036W