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Code
OSV00067W
$240USD
ID Tag
Rb1103-130909-WS
Immunogen
A synthetic peptide from the c-terminal region of mouse VTI1A (Vesicle transport v-SNARE protein Vti1-like 2) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Vesicle transport through interaction with t-SNAREs homolog 1A, Vesicle transport v-SNARE protein Vti1-like 2, Vti1-rp2
Target
FUNCTION: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
SUBCELLULAR LOCATION: Membrane; Single-pass type IV membrane protein. Cytoplasmic vesicle ⺠secretory vesicle ⺠synaptic vesicle membrane; Single-pass type IV membrane protein. Cytoplasmic vesicle ⺠clathrin-coated vesicle membrane; Single-pass type IV membrane protein. Note: Enriched in small synaptic vesicles and clathrin-coated vesicles from nerve terminals. Isoform 1/VTI1A localizes to the cell bodies of hippocampal neurons as well as to nerve terminals.
Tissue specificity: Specifically expressed in the neuronal tissues cerebellum, cortex and hippocampus. Isoform 1 VTI1A is expressed in the same neuronal tissues but also in lung, liver, kidney and spleen.
SUBCELLULAR LOCATION: Membrane; Single-pass type IV membrane protein. Cytoplasmic vesicle ⺠secretory vesicle ⺠synaptic vesicle membrane; Single-pass type IV membrane protein. Cytoplasmic vesicle ⺠clathrin-coated vesicle membrane; Single-pass type IV membrane protein. Note: Enriched in small synaptic vesicles and clathrin-coated vesicles from nerve terminals. Isoform 1/VTI1A localizes to the cell bodies of hippocampal neurons as well as to nerve terminals.
Tissue specificity: Specifically expressed in the neuronal tissues cerebellum, cortex and hippocampus. Isoform 1 VTI1A is expressed in the same neuronal tissues but also in lung, liver, kidney and spleen.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Xu Y, et al. J. Biol. Chem. 273:21783-21789(1998)
2. Advani R.J, et al. J. Biol. Chem. 273:10317-10324(1998)
3. Carninci P, et al. Science 309:1559-1563(2005)
2. Advani R.J, et al. J. Biol. Chem. 273:10317-10324(1998)
3. Carninci P, et al. Science 309:1559-1563(2005)
Limitation
For research use only
Code
OSV00067W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for VTI1A.
Spcs X-react.
Mouse, human. Other species not yet tested but it is likely to work in rat.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSV00067W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to VTI1A
