Code
OSC00183G
$260USD
ID Tag
Rb2500-140415-WS
Immunogen
A synthetic peptide from human cFos protein conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in many other species including rat, mouse, hamster and cat.
Accession
Also known
Proto-oncogene protein cFOS, c-Fos
Target
FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
SUBUNIT: Heterodimer. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB
SUBCELLULAR LOCATION: Nucleus.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after purchase
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Hai T, et al. Genes Dev. 3:2083-2090(1989).
Limitation
For research use only
Related
products
Code
OSC00183G
$260USD
Unit size
500 ug
Purity
Whole serum
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal antibody
Isotype
Polyclonal, whole serum
Applications
IHC, WB. Use at a concentration of 2-5 ug/ml. The optimal concentration should be determined by the end user. Not yet tested in other applications. For WB tissue lysates prepared in the G1 lysing buffer is recommended (G1 lysing buffer is Ripa buffer containing 1% Triton-X100; 1% SDS and 1% SDC).
Specificity
Specific for cFOS.
Spcs X-react.
Rat, mouse, marmoset, human. Other species not yet tested.
Format
Lyophilised. This product contains 0.02% benzalkonium chloride.
Reconstitution
Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material.