CACNA2D3 antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

G Protein Signaling

Hydra Proteins

Immunology

Ion Channels & pumps

Microbiology

Neuroscience

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSC00182W

$240USD

ID Tag

Gt194-270909-WS

Immunogen

A synthetic peptide from the internal region of human CACNA2D3 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is identical in mouse and rat.

Accession

CACNA2D3_HUMAN
CACNA2D3_MOUSE
CACNA2D3_RAT

Also known

Voltage-dependent calcium channel subunit alpha-2/delta-3, Voltage-gated calcium channel subunit alpha-2/delta-3

Target

FUNCTION: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) but not T-type (CACNA1G).
Subcellular location: Membrane; Single-pass type I membrane protein
Miscellaneous: In contrast to CACNA2D1 and CACNA2D2, it does not bind gabapentin, an antiepileptic drug.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Hanke S, et al. Gene 264:69-75(2001)
2. Qin N, et al. Mol. Pharmacol. 62:485-496(2002)
3. Gong H.C, et al. J. Membr. Biol. 184:35-43(2001)

Limitation

For research use only

Code

OSC00182W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

Goat

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for CACNA2D3.

Spcs X-react.

Human, mouse, rat. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSC00182W