Toll-like receptor 9 antibody, TLR9 antibody, CD289 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OST00315W

$240USD

ID Tag

Gt187-270909-WS

Immunogen

A synthetic peptide from aa region 830-880 of human TLR9 conjugated to blue carrier protein was used as the antigen.

Accession

TLR9_HUMAN

Also known

Toll-like receptor 9

Target

FUNCTION: Participates in the innate immune response to microbial agents. Detects the unmethylated cytidine-phosphate-guanosine (CpG) motifs present in bacterial DNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein.
TISSUE SPECIFICITY: Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Du X, et al. Eur. Cytokine Netw. 11:362-371(2000)
2. Hemmi H, et al. Nature 408:740-745(2000)

Limitation

For research use only

Related
products

Code	Product Name
OST00299G	Rabbit antibody to TLR9 (830-880)
OST00297W	Rabbit antibody to TLR9 (830-880)

Code

OST00315W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

Goat

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB, Flow Cyt. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for TLR9.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Code

OST00297P

$120USD

ID Tag

68912-57

Unit size

50 Âµg

Accession

TLR9_HUMAN

Also known

Toll-like receptor 9

Target

This is the immunising peptide for the products Rabbit antibody to TLR9 (830-880) (OST00297W, OST00299G) and Goat antibody to TLR9 (830-880) (OST00315W)

Purity

>85%

Applications

Control peptide

Format

Lyophilised

Reconstitution

This peptide is soluble in water and PBX.

Storage

Maintain refrigerated at 2-8°C for up to 12 months. After reconstitution keep at -20°C. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

Limitation

For research use only