Toll-like receptor 7 antibody, TLR7 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OST00314W

$240USD

ID Tag

Gt186-270909-WS

Immunogen

A synthetic peptide from the extracellular domain of human TLR7 conjugated to an immunogenic carrier protein was used as the antigen.

Accession

TLR7_HUMAN

Also known

Toll-like receptor 7

Target

FUNCTION: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein.
TISSUE SPECIFICITY: Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Du X, et al. Eur. Cytokine Netw. 11:362-371(2000)
2. Clark H.F, et al. Genome Res. 13:2265-2270(2003)

Limitation

For research use only

Related
products

Code	Product Name
OST00296W	Rabbit antibody to TLR7

Code

OST00314W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

Goat

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB, Flow Cyt. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for TLR7.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OST00314W