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Code
OSP00090W
$240USD
ID Tag
Gt185-270909-WS
Immunogen
A synthetic peptide from the c-terminal region of human Pr3 (Leukocyte proteinase 3, AGP7, Myeloblastin, Wegener autoantigen) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Leukocyte proteinase 3, AGP7, Myeloblastin, Wegener autoantigen, PR-3, P29, C-ANCA antigen, Neutrophil proteinase 4, MBN, PRTN3, NP-4
Target
FUNCTION: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
Catalytic activity: Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-.
Catalytic activity: Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Labbaye C, et al. Proc. Natl. Acad. Sci. U.S.A. 88:9253-9256(1991)
2. Grimwood J, et al. Nature 428:529-535(2004)
3. Fujinaga M, et al. J. Mol. Biol. 261:267-278(1996)
4. Duke-Cohan J.S, et al. J. Biol. Chem. 270:14107-14114(1995)
5. Jenne D.E, et al. Nature 346:520-520(1990)
2. Grimwood J, et al. Nature 428:529-535(2004)
3. Fujinaga M, et al. J. Mol. Biol. 261:267-278(1996)
4. Duke-Cohan J.S, et al. J. Biol. Chem. 270:14107-14114(1995)
5. Jenne D.E, et al. Nature 346:520-520(1990)
Limitation
For research use only
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Code
OSP00090W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
Goat
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
WB, IHC, flow cytometry. A dilution of 1: 200 to 1: 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Pr3.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSP00090W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
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Goat antibody to Pr3
