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Code
OSS00179W
$240USD
ID Tag
Rb1136-260909-WS
Immunogen
A synthetic peptide from aa region 595-645of human Synapsin 1 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Synapsin 1, Syn1, Synapsin I
Target
May act as an anchoring protein by linking the vesicle phospholipid layer and the cytoskeleton in neuronal presynaptic terminals; may play a role in neurotransmitter release.
FUNCTION: Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
SUBCELLULAR LOCATION: Cell junction, synapse. Golgi apparatus.
FUNCTION: Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
SUBCELLULAR LOCATION: Cell junction, synapse. Golgi apparatus.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Ross M.T, et al. Nature 434:325-337(2005)
2. Matsuoka S, et al. Science 316:1160-1166(2007)
2. Matsuoka S, et al. Science 316:1160-1166(2007)
Limitation
For research use only
Code
OSS00179W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 2000 to 1 : 4000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Synapsin-1.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
- Click to see the eLab Book
Code
OSS00179W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSS00179W
$240USD
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WB on brain lysates. Blocking with 1% LFDM for 30 min at RT; Primary antibody used at 1:3000 dilution incubated overnight at 4C. Click on eLAB BOOK tab to see the details. |
⚬ Products
Rabbit antibody to Synapsin 1 (595-645)
