Rb1107-130909-WS

A synthetic peptide from n-terminal region of human Complexin-3 conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 90% identity with Complexin-4.

CPLX3_HUMAN
CPLX3_MOUSE
CPLX4_HUMAN
CPLX4_MOUSE

CPLX3, Complexin III, Complexin 3; CPLX4, Complexin-4, Complexin 4, Complexin IV

FUNCTION: Complexin-3 & 4: Positively regulates a late step in synaptic vesicle exocytosis.
SUBCELLULAR LOCATION: Cytoplasm › cytosol. Note: Enriched at synaptic-releasing sites in mature neurons.
Tissue specificity: Complexin-3: Present in many brain regions, including hippocampus and cerebellum. In the retina, present both at conventional amacrine cell synapses and at photoreceptor ribbon synapses (at protein level).
Complexin-4: Present specifically in the retina, at rod photoreceptor ribbon synapses. Not expressed at conventional amacrine cell synapses, nor at cone photoreceptor ribbon synapses (at protein level).
Subcellular location: Complexin-3 & 4: Membrane; Lipid-anchor. Cell junction › synapse. Note: Enriched at the synaptic terminal.

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

12 months after reconstitution

This item will be shipped to you at ambient temperature in a lyophilised form.

1. Reim K, et al. J. Cell Biol. 169:669-680(2005)
2. Ohira M, et al. Cancer Lett. 197:63-68(2003)

For research use only

100 µl

Unconjugated antibody

NZ white rabbit

Whole serum

Polyclonal

Polyclonal, whole serum

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specific for Complexin-3 & 4.

Human, mouse. Other species not yet tested.

Lyophilised

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

- Click to download the Data Sheet

- Click to download the Material Safety Data Sheet