Code
OSS00173W
$240USD
ID Tag
Rb1096-130909-WS
Immunogen
A synthetic peptide from n-terminal region of human Syntaxin-4 (STX4A, STX4) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
STX4, Renal carcinoma antigen NY-REN-31, STX4A
Target
FUNCTION: Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. May also play a role in docking of synaptic vesicles at presynaptic active zones.
SUBCELLULAR LOCATION: Cell membrane; Single-pass type IV membrane protein
TISSUE SPECIFICITY: Expressed in neutrophils and neutrophil-differentiated HL-60 cells. Expression in neutrophils increases with differentiation.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Li H, et al. Gene 143:303-304(1994)
2. Heibeck T.H, et al. J. Proteome Res. 8:3852-3861(2009)
Limitation
For research use only
Code
OSS00173W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Syntaxin-4.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.