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Code
OSS00167W
$240USD
ID Tag
Rb1089-130909-WS
Immunogen
A synthetic peptide from n-terminal region of mouse Synaptosomal-associated protein 23 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 90% identity with SNAP-25.
Accession
Also known
SNP23, Synaptosomal-associated protein 23, Vesicle-membrane fusion protein SNAP-23, Syndet; SNP25, Synaptosomal-associated protein 25, Vesicle-membrane fusion protein SNAP-25, SUP, SNAP
Target
FUNCTION: SNAP-23: Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
SNAP-25: t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
SUBCELLULAR LOCATION: SNAP-23: Cell membrane; Peripheral membrane protein. Cell junction ⺠synapse ⺠synaptosome. Note: Mainly localized to the plasma membrane.
SNAP-25: Cytoplasm ⺠perinuclear region. Cell membrane; Lipid-anchor. Cell junction ⺠synapse ⺠synaptosome. Note: Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region.
SNAP-25: t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
SUBCELLULAR LOCATION: SNAP-23: Cell membrane; Peripheral membrane protein. Cell junction ⺠synapse ⺠synaptosome. Note: Mainly localized to the plasma membrane.
SNAP-25: Cytoplasm ⺠perinuclear region. Cell membrane; Lipid-anchor. Cell junction ⺠synapse ⺠synaptosome. Note: Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Araki S, et al. Biochem. Biophys. Res. Commun. 234:257-262(1997)
2. Vaidyanathan V.V, et al. Gene 247:181-189(2000)
3. Wang C.-C, et al. Dev. Cell 7:359-371(2004)
2. Vaidyanathan V.V, et al. Gene 247:181-189(2000)
3. Wang C.-C, et al. Dev. Cell 7:359-371(2004)
Limitation
For research use only
Code
OSS00167W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SNAP-23 and SNAP-25.
Spcs X-react.
Mouse, rat, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00167W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to SNAP-23 and SNAP-25
