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Code
OSA00109W
$240USD
ID Tag
Rb1077-020809-WS
Immunogen
A synthetic peptide from aa region 710-760 of human PMCA1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Accession
Also known
AT2B1, Plasma membrane calcium-transporting ATPase 1, PMCA1, Plasma membrane calcium pump isoform 1, ATP2B1
Target
FUNCTION: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Isoform B is ubiquitously expressed. Isoform c is found in brain cortex, skeletal muscle and heart muscle. Isoform D has only been found in fetal skeletal muscle. Isoform k has been found in small intestine and liver.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Isoform B is ubiquitously expressed. Isoform c is found in brain cortex, skeletal muscle and heart muscle. Isoform D has only been found in fetal skeletal muscle. Isoform k has been found in small intestine and liver.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Verma A.K, et al. J. Biol. Chem. 263:14152-14159(1988)
2. Olsen J.V, et al. Cell 127:635-648(2006)
2. Olsen J.V, et al. Cell 127:635-648(2006)
Limitation
For research use only
- Click to download the Data Sheet
⚬ Products
Rabbit antibody to PMCA1 (710-760)
