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Code
OSG00049W
$260USD
ID Tag
Rb1073-020809-WS
Immunogen
A synthetic peptide from c-terminal region of mouse Glucose transporter type 10 (GLUT10) conjugated to blue carrier protein was used as the antigen.
Accession
Also known
GTR10, Solute carrier family 2, facilitated glucose transporter member 10, GLUT-10, SLC2A10, GLUT10
Target
FUNCTION: Facilitative glucose transporter.
SUBCELLULAR LOCATION: Endomembrane system; Multi-pass membrane protein. Cytoplasm ⺠perinuclear region.
TISSUE SPECIFICITY: Widely expressed; highest levels in liver and pancreas.
Involvement in disease: Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS). ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.
SUBCELLULAR LOCATION: Endomembrane system; Multi-pass membrane protein. Cytoplasm ⺠perinuclear region.
TISSUE SPECIFICITY: Widely expressed; highest levels in liver and pancreas.
Involvement in disease: Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS). ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Dawson P.A, et al. Mol. Genet. Metab. 74:186-199(2001)
Limitation
For research use only
Code
OSG00049W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for GLUT-10.
Spcs X-react.
Mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSG00049W
$260USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to GLUT10 (SLC2A10)
