Code
OSV00061W
$240USD
ID Tag
Rb1070-020809-WS
Immunogen
A synthetic peptide from aa region 460-510 of human VMAT2 conjugated to blue carrier protein was used as the antigen. The antigen shares 89% identity with rat and mouse sequences.
Accession
Also known
VMAT2, Synaptic vesicular amine transporter, VAT2, Monoamine transporter, Solute carrier family 18 member 2, SLC18A2, SVMT, VMAT2
Target
FUNCTION: Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.
SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Surratt C.K, et al. FEBS Lett. 318:325-330(1993)
2. Erickson J.D, et al. J. Neurochem. 61:2314-2317(1993)
Limitation
For research use only
Code
OSV00061W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for VMAT2.
Spcs X-react.
Human. Other species not yet tested but likely to work in rat and mouse.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.