ER Marker, ER Marker antibody, Calreticulin antibody, Calregulin antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSC00165W

$240USD

ID Tag

Rb1026-280609-WS

Immunogen

A synthetic peptide from the c-terminal region of human Calreticulin (Calregulin) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

CALR_HUMAN
CALR_RAT
CALR_MOUSE

Also known

CALR, CRP55, Calregulin, HACBP, ERp60, grp60, CRTC

Target

FUNCTION: Molecular calcium binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export.
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen. Cytoplasm âº cytosol. Secreted âº extracellular space âº extracellular matrix. Cell surface. Note: Also found in cell surface (T cells), cytosol and extracellular matrix. Associated with the lytic granules in the cytolytic T-lymphocytes.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. McCauliffe D.P, et al. J. Clin. Invest. 85:1379-1391(1990)
2. Rokeach L.A, et al. J. Immunol. 147:3031-3039(1991)
3. Choudhary C, et al. Science 325:834-840(2009)

Limitation

For research use only

Code

OSC00165W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for Calreticulin.

Spcs X-react.

Human, rat, mouse. Not yet tested in other species.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSC00165W