Calnexin antibody, ER marker antibody, ER membrane marker antibody, CANX

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSC00161W

$240USD

ID Tag

Rb1022-280609-WS

Immunogen

A synthetic peptide from the lumenal region of human Calnexin (MHC I antigen-binding protein p88) conjugated to an immunogenic carrier protein was used as the immunogen.

Accession

CALX_HUMAN
CALX_RAT
CALX_MOUSE

Also known

CANX, CALX, Major histocompatibility complex class I antigen-binding protein p88, p90, IP90

Target

FUNCTION: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. David V, et al. J. Biol. Chem. 268:9585-9592(1993)
2. Ota T, et al. Nat. Genet. 36:40-45(2004)
3. Choudhary C, et al. Science 325:834-840(2009)

Limitation

For research use only

Code

OSC00161W

$240USD

Unit size

150 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for Calnexin.

Spcs X-react.

Human, rat, mouse, xenopus. Not yet tested in other species.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSC00161W