Code
OSP00085G
$240USD
ID Tag
Rb980-280609-G
Immunogen
A synthetic peptide from human P2RX7 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
P2RX7, P2X purinoceptor 7, Purinergic receptor, P2Z receptor, ATP receptor
Target
FUNCTION: Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
Subcellular location: Membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Chessell I.P, et al. FEBS Lett. 439:26-30(1998)
2. Rassendren F, et al. J. Biol. Chem. 272:5482-5486(1997)
Limitation
For research use only
Related
products
Code
OSP00085G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for P2RX7.
Spcs X-react.
Mouse, human, rat, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.