Code
OSL00009W
$240USD
ID Tag
Rb1020-280609-WS
Immunogen
A synthetic peptide from the n-terminal region of human Lamin-A/C conjugated to blue carrier protein was used as the antigen. The peptide is homologous in many other species.
Accession
Also known
Lamin-A/C, Lamin A/C, Lamin A / C, LaminA/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1
Target
FUNCTION: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals.
SUBCELLULAR LOCATION: Nucleus
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. McKeon F.D, et al. Nature 319:463-468(1986)
2. Gregory S.G, et al. Nature 441:315-321(2006)
Limitation
For research use only
Code
OSL00009W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Lamin-A/C.
Spcs X-react.
Human, rat, mouse. Not yet tested in other species.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.