Code
OSP00076W
$240USD
ID Tag
Rb999-280609-WS
Immunogen
A synthetic peptide from aa region 100-150 of human KCNH3 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Potassium voltage-gated channel subfamily H member 3, Voltage-gated potassium channel subunit Kv12.2, Ether-a-go-go-like potassium channel 2, ELK channel 2, ELK2, Brain-specific eag-like channel 1, BEC1
Target
Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly.
Tissue specificity: Detected only in brain, in particular in the telencephalon. Detected in the cerebral cortex, occipital pole, frontal and temporal lobe, putamen, amygdala, hippocampus and caudate nucleus.
Subcellular location: Membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Miyake A, et al. J. Biol. Chem. 274:25018-25025(1999)
2. Nagase T, et al. DNA Res. 6:337-345(1999)
Limitation
For research use only
Code
OSP00076W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for KCNH3.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.