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Code
OSP00073W
$240USD
ID Tag
Rb990-280609-WS
Immunogen
A synthetic peptide from the cytoplasmic domain of human KCNE3 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Potassium voltage-gated channel subfamily E member 3, Minimum potassium ion channel-related peptide 2, Potassium channel subunit beta MiRP2, MinK-related peptide 2
Target
Function: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion.
Tissue specificity: Widely expressed with highest levels in kidney and moderate levels in small intestine.
Subcellular location: Membrane; Single-pass type I membrane protein.
Tissue specificity: Widely expressed with highest levels in kidney and moderate levels in small intestine.
Subcellular location: Membrane; Single-pass type I membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Melman Y.F, et al. J. Biol. Chem. 276:6439-6444(2001)
5. Ohno S, et al. Hum. Mutat. 30:557-563(2009)
5. Ohno S, et al. Hum. Mutat. 30:557-563(2009)
Limitation
For research use only
Code
OSP00073W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for KCNE3.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSP00073W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to KCNE3
