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Code
OSP00060W
$240USD
ID Tag
Sh160-280609-WS
Immunogen
A synthetic peptide from the n-terminal region of human Pr3 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Leukocyte proteinase 3, AGP7, Myeloblastin, Wegener autoantigen, PR-3, P29, C-ANCA antigen, Neutrophil proteinase 4, MBN, PRTN3, NP-4
Target
FUNCTION: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
Catalytic activity: Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-.
Catalytic activity: Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Labbaye C, et al. Proc. Natl. Acad. Sci. U.S.A. 88:9253-9256(1991)
2. Grimwood J, et al. Nature 428:529-535(2004)
2. Grimwood J, et al. Nature 428:529-535(2004)
Limitation
For research use only
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