SCN8A antibody, Nav1.6 antibody, Sodium channel protein type 8 subunit alpha antibody

Primary Antibodies

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSS00153W

$240USD

ID Tag

Rb940-240509-WS

Immunogen

A synthetic peptide from the internal region of mouse Nav1.6 (SCN8A) conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and human.

Accession

SCN8A_MOUSE
SCN8A_RAT
SCN8A_HUMAN

Also known

Sodium channel protein type VIII subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.6, SCN8A, MED, Nav1.6

Target

FUNCTION: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na⁺ ions may pass in accordance with their electrochemical gradient.
Tissue specificity: Expressed in brain, cerebellum and spinal cord.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Plummer N.W, et al. J. Biol. Chem. 272:24008-24015(1997)
2. Plummer N.W, et al. Genomics 54:287-296(1998)

Limitation

For research use only

Code

OSS00153W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for SCN8A.

Spcs X-react.

Human, rat, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSS00153W