Code
OSS00150W
$240USD
ID Tag
Rb937-240509-WS
Immunogen
A synthetic peptide from mouse Nav1.4 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in human and rat.
Accession
Also known
Sodium channel protein type IV subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.4, Sodium channel protein skeletal muscle subunit alpha, SkM1, SCN4A
Target
FUNCTION: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. George A.L. Jr, et al. Ann. Neurol. 31:131-137(1992)
Limitation
For research use only
Code
OSS00150W
$240USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Nav1.4.
Spcs X-react.
Human, mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.