Code
OSS00149W
$240USD
ID Tag
Rb936-240509-WS
Immunogen
A synthetic peptide from the c-terminal of human Sodium channel protein type 3 subunit alpha (SCN3A, Nav1.3) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Sodium channel protein type III subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.3, Sodium channel protein, brain III subunit alpha, Voltage-gated sodium channel subtype III, SCN3A, NAC3
Target
FUNCTION: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Rougier J.-S, et al. Am. J. Physiol. 288:C692-C701(2005)
2. Kasai N, et al. Gene 264:113-122(2001)
Limitation
For research use only
Code
OSS00149W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SCN3A.
Spcs X-react.
Human. Other species not yet tested, but expected in work in mouse and rat.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.