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Code
OSK00043W
$240USD    Buy Now 

ID Tag
Rb914-260409-WS

Immunogen
A synthetic peptide from the c-terminal region of rat KCNK6 (TOSS, TWIK2) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

Also known
Potassium channel subfamily K member 6, Inward rectifying potassium channel protein TWIK-2, TWIK-originated similarity sequence, TOSS, TWIK2

Target
Function: Exhibits outward rectification in a physiological K+ gradient and mild inward rectification in symmetrical K+ conditions. Inhibited by internal acidification and, to a small degree, by zinc. Not inhibited by quinine, quinidine or barium.
Tissue specificity: Widespread expression, detected in all tissues tested except for skeletal muscle. Strongest expression in placenta, pancreas, heart, colon and spleen, lower levels detected in peripheral blood leukocytes, lung, liver, kidney and thymus. Lowest expression detected in brain.
Subcellular location: Membrane, Multi-pass membrane protein.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Patel A.J, et al. J. Biol. Chem. 275:28722-28730(2000)
2. Carninci P, et al. Methods Enzymol. 303:19-44(1999)
3. Okazaki Y, et al. Nature 420:563-573(2002)

Limitation
For research use only

⚬ Products
Rabbit antibody to KCNK6
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
Tissue lysate preparation
G2 Lysing Buffer
R Lysing Buffer
G3 Lysing Buffer
G4 Lysing Buffer
G5 Lysing Buffer
G6 Lysing Buffer
Content

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