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Code
OSK00041W
$240USD
ID Tag
Rb912-260409-WS
Immunogen
A synthetic peptide from the c-terminal region of human KCNK5 (TASK2) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Potassium channel subfamily K member 5, Acid-sensitive potassium channel protein TASK-2, TWIK-related acid-sensitive K(+) channel 2, KCNK5, TASK2
Target
Function: pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K+ concentrations. Inhibited by quinine, quinidine and external acidification.
Tissue specificity: Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli.
Subcellular location: Membrane, Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Reyes R, et al. J. Biol. Chem. 273:30863-30869(1998)
2. Gierten J, et al. Br. J. Pharmacol. 154:1680-1690(2008)
3. Mungall A.J, et al. Nature 425:805-811(2003)
4. Niemeyer M.I, et al. Mol. Membr. Biol. 20:185-191(2003)
5. Daub H, et al. Mol. Cell 31:438-448(2008)
2. Gierten J, et al. Br. J. Pharmacol. 154:1680-1690(2008)
3. Mungall A.J, et al. Nature 425:805-811(2003)
4. Niemeyer M.I, et al. Mol. Membr. Biol. 20:185-191(2003)
5. Daub H, et al. Mol. Cell 31:438-448(2008)
Limitation
For research use only
Code
OSK00041W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for KCNK5.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSK00041W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
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Rabbit antibody to KCNK5
