VTA1 antibody, SBP1 antibody, LIP5 antibody, Vacuolar protein sorting associated protein antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSV00049W

$240USD

ID Tag

Rb797-140209-WS

Immunogen

A synthetic peptide from the internal region of human VTA1 conjugated to an immunogenic carrier protein was used as the antigen.

Accession

VTA1_HUMAN

Also known

Vacuolar protein sorting-associated protein VTA1 homolog, Dopamine-responsive protein DRG-1, SKD1 binding protein 1, SBP1, LYST-interacting protein 5, LIP5

Target

FUNCTION: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding.
SUBCELLULAR LOCATION: Cytoplasm. Endosome membrane; Peripheral membrane protein

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1.Zhang Q.-H, et al. Genome Res. 10:1546-1560(2000)
2. Wiemann S, et al. Genome Res. 11:422-435(2001)

Limitation

For research use only

Code

OSV00049W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 500 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.

Specificity

Specific for VTA1.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSV00049W