|
|
Code
OSK00027G
$240USD
ID Tag
Rb871-290309-G
Immunogen
A synthetic peptide from aa region 850-900 the of human KCNH2 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in mouse and rat.
Accession
Also known
Potassium voltage-gated channel subfamily H member 2, Voltage-gated potassium channel subunit Kv11.1, Ether-a-go-go-related gene potassium channel 1, H-ERG, Erg1, Ether-a-go-go-related protein 1, Eag-related protein 1, eag homolog, ERG, ERG1, HERG, HERG1
Target
FUNCTION: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Isoform 1 is expressed in heart, brain and testis and at low levels in lung. Isoform 3 is expressed predominantly in heart. The expression of isoform 2 is low in all tissues tested.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Isoform 1 is expressed in heart, brain and testis and at low levels in lung. Isoform 3 is expressed predominantly in heart. The expression of isoform 2 is low in all tissues tested.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. London B, et al. Circ. Res. 81:870-878(1997)
2. Lees-Miller J.P, et al. Circ. Res. 81:719-726(1997)
2. Lees-Miller J.P, et al. Circ. Res. 81:719-726(1997)
Limitation
For research use only
Related
products
products
|
Code
OSK00027G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB (confirmed by recombinant protein). A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for KCNH2.
Spcs X-react.
Rat, mouse, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSK00027G
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to KCNH2 (850-900)
