Code
OSH00016W
$240USD
ID Tag
Rb845-290309-WS
Immunogen
A synthetic peptide from aa region 39-59 of pro region of mouse Hepcidin conjugated to blue carrier protein has been used as the antigen.
Accession
Also known
Hepcidin, Liver-expressed antimicrobial peptide, LEAP-1, Putative liver tumor regressor, HAMP, HEPC, LEAP1
Target
FUNCTION: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity.
SUBCELLULAR LOCATION: Secreted.
Tissue specificity: Highly expressed in the liver and to a much lesser extent in the heart.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Pigeon C, et al. J. Biol. Chem. 276:7811-7819(2001)
2. Nicolas G, et al. Proc. Natl. Acad. Sci. U.S.A. 98:8780-8785(2001)
Limitation
For research use only
Related
products
Code
OSH00016W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. Use at a dilution of 1:100 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Hepcidin.
Spcs X-react.
Mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.