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Code
OSG00042G
$240USD
ID Tag
Sh136-070309-G
Immunogen
A synthetic peptide from the VHS domain of human GGA3 conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat, mouse, chicken.
Accession
Also known
ADP-ribosylation factor-binding protein GGA3; Golgi-localized, gamma ear-containing, ARF-binding protein 3; Gamma-adaptin-related protein 3
Target
FUNCTION: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
TISSUE SPECIFICITY: Ubiquitously expressed.
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
TISSUE SPECIFICITY: Ubiquitously expressed.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Takatsu H, et al. Biochem. J. 365:369-378(2002).
2. Puertollano R, et al. Science 292:1712-1716(2001).
3. Doray B, et al. Proc. Natl. Acad. Sci. U.S.A. 99:8072-8077(2002).
2. Puertollano R, et al. Science 292:1712-1716(2001).
3. Doray B, et al. Proc. Natl. Acad. Sci. U.S.A. 99:8072-8077(2002).
Limitation
For research use only
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Code
OSG00042G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
Sheep
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for GGA3.
Spcs X-react.
Mouse, rat, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSG00042G
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
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Sheep antibody to GGA3
