TRPC6 antibody

Primary Antibodies

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OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS
IMAGES

Code

OST00276G

$240USD

ID Tag

Rb618-170808-G

Immunogen

A synthetic peptide from taa region 10-60 of rat TRPC6 conjugated to blue carrier protein was used as the antigen. The antigen is homologous with the corresponding sequence in mouse.
The location of the epitope is highlighted in green.

Accession

TRPC6_MOUSE
TRPC6_RAT

Also known

Short transient receptor potential channel 6, TrpC6, Calcium entry channel, Trp6, transient receptor potential cation channel, subfamily C, member 6, Trrp6, mtrp6

Target

FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Boulay G, et al. J. Biol. Chem. 272:29672-29680(1997).

Limitation

For research use only

Related
products

Code	Product Name
OST00197W	Rabbit antibody to TRPC6 (10-60)

Code

OST00276G

$240USD

Unit size

500 Âµg

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

IgG

Clonality

Polyclonal

Isotype

Polyclonal, IgG

Applications

WB. A concentration of 3-10 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for TRPC6.

Spcs X-react.

Mouse, rat. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OST00276G