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Code
OSZ00004G
$240USD
ID Tag
Rb799-140209-G
Immunogen
A synthetic peptide from c-terminal region of human ZIC3 (Zinc finger protein ZIC 3) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many species including rat and mouse.
Accession
Also known
HTX, HTX1, Zic family member 3 (odd-paired Drosophila homolog heterotaxy 1), Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3), ZNF203
Target
Function: Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation.
Defects in ZIC3 are the cause of X-linked visceral heterotaxy (HTX1). HTX1 is a disease characterized by congenital heart disease and alterations of visceral situs, including asplenia or polysplenia, symmetric liver, intestinal malrotation, and abnormal lung lobation.
Defects in ZIC3 are the cause of X-linked visceral heterotaxy (HTX1). HTX1 is a disease characterized by congenital heart disease and alterations of visceral situs, including asplenia or polysplenia, symmetric liver, intestinal malrotation, and abnormal lung lobation.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Gebbia M, et al. Nat. Genet. 17:305-308(1997)
2. Ross M.T, et al. Nature 434:325-337(2005)
3. Ware S.M, et al. Am. J. Hum. Genet. 74:93-105(2004)
4. Sjoeblom T, et al. Science 314:268-274(2006)
5. Chhin B, et al. Hum. Mutat. 28:563-570(2007)
2. Ross M.T, et al. Nature 434:325-337(2005)
3. Ware S.M, et al. Am. J. Hum. Genet. 74:93-105(2004)
4. Sjoeblom T, et al. Science 314:268-274(2006)
5. Chhin B, et al. Hum. Mutat. 28:563-570(2007)
Limitation
For research use only
Related
products
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Code
OSZ00004G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ZIC1, 2, 3.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSZ00004G
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to ZIC1-3
