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Code
OSP00029W
$240USD
ID Tag
Rb779-140209-WS
Immunogen
A synthetic peptide from the cytoplasmic domain of human P2X1 conjugated to blue carrier protein was used as the antigen. The antigen shares 92% identity with rat and mouse sequence.
Accession
Also known
P2RX1, P2X1, P2X purinoceptor 1, ATP receptor
Target
FUNCTION: Ligand gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death.
Subcellular location: Membrane; Multi-pass membrane protein.
Involvement in disease: Defects in P2RX1 are a cause of bleeding disorder
Subcellular location: Membrane; Multi-pass membrane protein.
Involvement in disease: Defects in P2RX1 are a cause of bleeding disorder
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Valera S, et al. Recept. Channels 3:283-289(1995)
Limitation
For research use only
Code
OSP00029W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for P2RX1.
Spcs X-react.
Mouse, human, rat, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
- Click to see the eLab Book
Code
OSP00029W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSP00029W
$240USD
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WB on bladder lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:2000 incubated at 4C overnight. Click on eLAB BOOK tab to see the details. |
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Rabbit antibody to P2X1
