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Code
OSS00116G
$240USD
ID Tag
Rb1237-051209-G
Immunogen
A synthetic peptide from human SHANK3 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
SH3 and multiple ankyrin repeat domains protein 3, ProSAP2, Proline rich synapse associated protein 2, PSAP2
Target
Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
Subcellular location: Cytoplasm. Cell junction ⺠synapse. Cell junction ⺠synapse ⺠postsynaptic cell membrane ⺠postsynaptic density. Note: Postsynaptic density of neuronal cells. Extends into the region subjacent to the PSD.
Tissue specificity: Widely expressed in brain.
Subcellular location: Cytoplasm. Cell junction ⺠synapse. Cell junction ⺠synapse ⺠postsynaptic cell membrane ⺠postsynaptic density. Note: Postsynaptic density of neuronal cells. Extends into the region subjacent to the PSD.
Tissue specificity: Widely expressed in brain.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Dunham I, et al. ature 402:489-495(1999)
Limitation
For research use only
Related
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Code
OSS00116G
$240USD
Unit size
500 ug
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB. A concentration of 10-50 ug/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SHANK3.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00116G
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
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Rabbit antibody to SHANK3
