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Code
OSS00109W
$240USD
ID Tag
Rb2776-080616-WS
Immunogen
A synthetic peptide from mouse SUMO 1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in human, rat and marmoset.
Accession
Also known
Small ubiquitin-related modifier 1, SUMO-1, Sumo1
Target
Function: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4
Subcellular location: Nucleus. Cytoplasm
Post-translational modification: Cleavage of precursor form by SENP1 or SENP2 is necessary for function.
Subcellular location: Nucleus. Cytoplasm
Post-translational modification: Cleavage of precursor form by SENP1 or SENP2 is necessary for function.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Um J.W, et al. J. Neurosci. Res. 84:1543-1554(2006)
Limitation
For research use only
Related
products
products
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Code
OSS00109W
$240USD
Unit size
150 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 500 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for SUMO1.
Spcs X-react.
Rat, mouse, human, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 150 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
- Click to see the eLab Book
Code
OSS00109W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSS00109W
$240USD
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WB on rat brain lysate. Lysate was prepared in Ripa containing 1% Triton X-100, 1% SDS and 1% SDC. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:500 incubated at 4C overnight. Click on eLAB BOOK tab to see the details. |
⚬ Products
Rabbit antibody to SUMO1
