Code
OSC00073W
$240USD
ID Tag
Rb1447-120610-WS
Immunogen
A synthetic peptide from aa region 600-650 of rat CNGA2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and human.
Accession
Also known
Cyclic nucleotide-gated olfactory channel, Cyclic nucleotide-gated cation channel 2, CNG channel alpha-2, CNG-2, CNG2, CNCA, CNCA1, CNCG2
Target
Function: Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.
Subunit structure: Heterooligomer of OCNC1 and OCNC2 subunits.
Subcellular location: Membrane; Multi-pass membrane protein.
Tissue specificity: Olfactory neurons.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Dhallan R.S, et al. Nature 347:184-187(1990)
2. Sjoeblom T, et al. Science 314:268-274(2006)
Limitation
For research use only
Code
OSC00073W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for CNGA2.
Spcs X-react.
Rat, mouse, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.