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Code
OSA00061G
$240USD
ID Tag
Rb1410-250410-G
Immunogen
A synthetic peptide from rat Arg3.1 (ARC) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein homolog, Arg3.1/ARC
Target
FUNCTION: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Endosome. Acrosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse. Note: associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Endosome. Acrosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse. Note: associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Tan J, et al. Neuroscience. 16;145(2):715-26(2007).
2. Link,W, et al. Proc. Natl. Acad. Sci. U.S.A. 92 (12), 5734-5738 (1995).
3. Shepherd J.D, et al. Neuron 52:475-484(2006).
4. Rial Verde E.M, et al. Neuron 52:461-474(2006).
5. Chowdhury S, et al. Neuron 52:445-459(2006).
2. Link,W, et al. Proc. Natl. Acad. Sci. U.S.A. 92 (12), 5734-5738 (1995).
3. Shepherd J.D, et al. Neuron 52:475-484(2006).
4. Rial Verde E.M, et al. Neuron 52:461-474(2006).
5. Chowdhury S, et al. Neuron 52:445-459(2006).
Limitation
For research use only
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Code
OSA00061G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user.
Specificity
Specific for Arg3.1/ARC.
Spcs X-react.
Human, mouse and rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSA00061G
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
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