phospho S271 & S274 of CREM antibody, CREM antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSC00064W

$260USD

ID Tag

Sh110-060908-WS

Immunogen

A synthetic peptide to phospho S271 & S274 of human CREM (cAMP-responsive element modulator, Inducible cAMP early repressor, ICER) conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat, mouse and dog.

Accession

CREM_HUMAN
CREM_RAT
CREM_MOUSE

Also known

cAMP-responsive element modulator, Inducible cAMP early repressor, ICER

Target

FUNCTION: Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation.
SUBUNIT: Binds DNA as a dimer. Interacts with FHL5.
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Expressed in testes (round spermatids) (at protein level). Isoform 14 is the major activator form in testes.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Masquilier D, et al. Cell Growth Differ. 4:931-937(1993).

Limitation

For research use only

Code

OSC00064W

$260USD

Unit size

100 ul

Conjugate

Unconjugated antibody

Host

Sheep

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. This antibody may also recognise the unphosphorylated form.

Specificity

Specific for CREM.

Spcs X-react.

Human, rat, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSC00064W