Anti Cofilin 1 antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSC00051W

$240USD

ID Tag

Sh102-060908-WS

Immunogen

A synthetic peptide from the phospho Y140 & S156 of human Cofilin-1 (Cofilin, non-muscle isoform) conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat, mouse and monkey.

Accession

COF1_HUMAN
COF1_RAT
COF1_MOUSE
COF1_MONKEY

Also known

Cofilin, non-muscle isoform

Target

FUNCTION: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
SUBCELLULAR LOCATION: Nucleus matrix. Cytoplasm, cytoskeleton. Note: Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.
TISSUE SPECIFICITY: Widely distributed in various tissues.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Ogawa K, et al. Nucleic Acids Res. 18:7169-7169(1990).
2. Rikova K, et al. Cell 131:1190-1203(2007).

Limitation

For research use only

Code

OSC00051W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

Sheep

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. This antibody may also recognice the unphosphorylated form. Not tested in other applications.

Specificity

Specific for Cofilin-1.

Spcs X-react.

Mouse, rat, human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSC00051W