VPS36 antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSV00032G

$240USD

ID Tag

Rb700-060908-G

Immunogen

A synthetic peptide from the internal region of mouse VPS36 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat.

Accession

VPS36_MOUSE
VPS36_RAT

Also known

VPS36

Target

FUNCTION: Component of the ESCRT-II complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL.
SUBCELLULAR LOCATION: Cytoplasm. Late endosome. Nucleus. NoteL Colocalizes with ubiquitinated proteins on late endosomes.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Carninci P, et al. Science 309:1559-1563(2005).
2. Gibbs R.A, et al. Nature 428:493-521(2004).
3. Kamura T, et al. J. Biol. Chem. 276:16528-16533(2001).

Limitation

For research use only

Related
products

Code	Product Name
OSV00031W	Rabbit antibody to VPS36

Code

OSV00032G

$240USD

Unit size

500 Âµg

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

IgG

Clonality

Polyclonal

Isotype

Polyclonal, IgG

Applications

IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Specificity

Specific for VPS36.

Spcs X-react.

Mouse, rat. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSV00032G