VPS29 antibody, Vacuolar protein sorting-associated protein 29 antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSV00030G

$240USD

ID Tag

Rb696-060908-G

Immunogen

A synthetic peptide from the c-terminal region of mouse VPS29 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat, human, chicken, zebra fish and xenopus.

Accession

VPS29_MOUSE
VPS29_RAT
VPS29_HUMAN

Also known

Vacuolar protein sorting-associated protein 29, Vesicle protein sorting 29, VPS29

Target

FUNCTION: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro).
CATALYTIC ACTIVITY: O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate.
COFACTOR: Binds 2 zinc ions per subunit.
SUBCELLULAR LOCATION: Cytoplasm. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Carninci P, et al. Science 309:1559-1563(2005).
2. Collins B.M, et al. Nat. Struct. Mol. Biol. 12:594-602(2005).

Limitation

For research use only

Related
products

Code	Product Name
OSV00029W	Rabbit antibody to VPS29

Code

OSV00030G

$240USD

Unit size

500 Âµg

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

IgG

Clonality

Polyclonal

Isotype

Polyclonal, IgG

Applications

IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Specificity

Specific for VPS29.

Spcs X-react.

Mouse, rat, human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSV00030G