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Code
OSM00057W
$240USD
ID Tag
Rb660-060908-WS
Immunogen
A synthetic peptide from mouse M6PR conjugated to blue carrier protein was used as the antigen.
Accession
Also known
CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, Cation-dependent mannose-6-phosphate receptor, M6pr, 46mpr
Target
FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
SUBUNIT: Homodimer. Binds GGA1, GGA2 and GGA3.
SUBCELLULAR LOCATION: Lysosome membrane; Single-pass type I membrane protein.
SUBUNIT: Homodimer. Binds GGA1, GGA2 and GGA3.
SUBCELLULAR LOCATION: Lysosome membrane; Single-pass type I membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Ludwig T, et al. J. Biol. Chem. 267:12211-12219(1992).
Limitation
For research use only
Related
products
products
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Code
OSM00057W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 3000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for M6PR.
Spcs X-react.
Mouse, rat, human, marmoset. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
- Click to see the eLab Book
Code
OSM00057W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSM00057W
$240USD
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WB on tissue lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:3000 incubated at 4C overnight. Click on eLAB BOOK tab to see the details. |
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Rabbit antibody to M6PR
