Code
OSG00024G
$240USD
ID Tag
Rb655-060908-G
Immunogen
A synthetic peptide from the n-terminal region of human Axonal membrane protein GAP-43 (Neuromodulin, growth-associated protein 43) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat, mouse, zebra fish and chicken.
Accession
Also known
Neuromodulin, growth-associated protein 43, protein F1, Basp2, B-50
Target
FUNCTION: This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.
SUBUNIT: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Note: Cytoplasmic surface of growth cone and synaptic plasma membranes.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Cimler B.M, et al. J. Biol. Chem. 262:12158-12163(1987).
2. Ballif B.A, et al. Mol. Cell. Proteomics 3:1093-1101(2004).
3. Vosseller K, et al. Proteomics 5:388-398(2005).
4. Trinidad J.C, et al. Mol. Cell. Proteomics 5:914-922(2006).
5. Munton R.P, et al. Mol. Cell. Proteomics 6:283-293(2007).
Limitation
For research use only
Related
products
Code
OSG00024G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user.
Specificity
Specific for GAP-43.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.