CRMP2 antibody, phospho T514 & S518 of CRMP-2 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSC00048W

$260USD

ID Tag

Sh98-060908-WS

Immunogen

A synthetic peptide from the phosphorylated sites of human T514 & S518 of CRMP2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat, mouse and chicken.

Accession

CRMP2_HUMAN
CRMP2_RAT
CRMP2_MOUSE
CRMP2_CHICKEN

Also known

Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, N2A3, DPYSL2, CRMP2

Target

FUNCTION: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
SUBUNIT: Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5. Interacts through its C-terminus with the C-terminus of CYFIP1/SRA1. Interacts with HTR4.
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Ubiquitous.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Goshima Y, et al. Nature 376:509-514(1995).

Limitation

For research use only

Related
products

Code	Product Name
OSC00046W	Rabbit antibody to phospho T514 & S518 CRMP2

Code

OSC00048W

$260USD

Unit size

100 ul

Conjugate

Unconjugated antibody

Host

Sheep

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. This antibody recognises mainly phospho T514 & S518 of CRMP-2 (but also it is quite likely to recognise the unphosphorylated form).

Specificity

Specific for CRMP2.

Spcs X-react.

Human, Mouse, rat. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSC00048W